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TheGMS is owned by Inovacus Publication (Inovacus). The journal includes original research on topics related to medical sciences, and publishes both quantitative and qualitative original research, reviews, case studies, retrospectives, editorials, discussion and analytical papers to facilitate continuing professional development in medical sciences.
Our Honorable Editors
Prof. Adel W Ekladious
Faculty of Health and Medical Sciences, Internal Medicine, The University of Western Australia, Australia
Dr. Kalliopi Megari
Neuropsychologist, School of Psychology & School of Medicine, Aristotle University of Thessaloniki, Greece.
Dr. Rama Shankar
Research Associate, Computational Biology, Michigan State University, USA
Dr. Luba Louise Ivanov
Professor, Chamberlain University, Illinois, US
Dr. Rasha Mosbah
Associate professor, Zagazig University, Egypt
Associate professor, Ahram Canadian university, Egypt
Dr. Sandeep Anand Padala
Assistant Professor, Augusta University Medical Center, Medical College of Georgia, US
Dr. Ray Marks
Department of Health and Behavior Studies, Columbia University, Teachers College, New York, US
Dr. Sanjib Kumar Guha
Postdoctoral Reasearch Associate, Department of Anesthesiology, University of Rochester Medical Center, USA
Recently published articles
Retrospective Study
Three-year epidemiological analysis of penetrating ocular traumatic endophthalmitis
This retrospective study analysed patients diagnosed as penetrating ocular traumatic endophthalmitis between January 2016 to January 2019 at a hospital, Liaoning province, China. Epidemiological data including age, gender, traumatic agents, time from trauma to endophthalmitis onset, culture results, treatment, visual acuity and prognosis. Risk factor analysis was used to compare presented data.
Case Report
Retina and optic nerve complications and hearing injury caused by Sclerotherapy of Facial Vascular Malformation
This report describes a complication of symptoms consistent with transiency visual acuity damage and hearing injury following sclerotherapy with a polidocanol injection to a facial vascular malformation. After the direct injection of 5cc polidocanol-room air emulsion into the subcutaneous malformation, a 3-year-old boy developed bilateral eyelid swelling the next day, and on 7 days later at referral, visual acuity in the left eye was light perception.
Review article
Cancer management during COVID-19 period-A preliminary study
The ongoing COVID-19 pandemic has now thrown us into turmoil by adversely affecting the entire socio-economic structure of the world. Currently (Dec 20, 2020), there are 76.4 million incidences worldwide and 17.6 million in the USA, and counting. Primarily in this scenario, all the resources available at hospitals and medical care units are reasonably redirected to address the contagious COVID-19 infected patients. This is an issue for a cancer patient, who may be at risk or infected with Coronavirus needs to be managed amid multiple unknown complications.
Case report
Pseudomeninocele after Laminectomy: Case report and literature review
Pseudomeningoceles are rare complications of laminectomy surgery. Such clinical condition results from an inadvertent surgical dural rupture. We describe in the present study the report of a patient who developed iatrogenic pseudomeningocele in the lumbar region after performing a left laminectomy in L5 topography. After the neurological assessment of the patient, bilateral hypoaesthesia was observed, in addition to a floating bulging in the lumbar region that was accentuated during the valsalva maneuver, with the hypothesis of a pseudomeningocele.
Prospective study
Tau aggregates possibly compromise neuronal health in the C. elegans model of Alzheimer’s
disease
Alzheimer’s disease (AD) is the most common degenerative brain disease in the aged population. By 2050, AD prevalence is expected to increase from 4.7 million (based on 2010 census) to 13.8 million people. It is characterized by the progressive decline of cognition and memory, as well as changes in behavior and personality. Pathological hallmarks of AD include mainly formation of senile plaques consisting of amyloid-beta (Aβ) peptide in the intercellular space and neurofibrillary tangles (NFTs) in the cell bodies, which are primarily composed of abnormally modified tau protein.
Research article
A one-year study of bacterial isolates causing Healthcare Acquired Infection (HAI) and their antibiotic resistance pattern at a private hospital in Egypt
The present study included 210 inpatients, out of them 180 were diagnosed as suspected cases of sepsis in the period over 12 months from December 2018 to December 2019, at a private hospital in Cairo, Egypt. Out of 210 investigated cases 180 (85.7%) were infected. Single bacterial isolates were recovered from 120 cases (66.7%), while 60 (33.3%) cases were found to be carrying more than one bacterial isolate. The results of the current study revealed that 34.4% (62/180) of isolates were Gram-positive and 65.6% (118/180) were Gram-negative.
Research article
Alzheimer’s Disease and COVID-19 fatalities linked to the NLRP3 inflammasome overregulation
To present a newsworthy hypothesis that illustrates how pollution predisposed long-term living and elderly population to an exacerbation of any preexisting inflammatory conditions, linked to NLRP3 inflammasome overregulation, in individuals with Alzheimer’s Disease (AD) and SARS-CoV-2 infections. Also, to discuss the possibility of correlation between AD/SARS-CoV-2 infection and air pollution.
Research article
A simple immunohistochemical method for detecting microglia in rat brain
This simple method specifically stained ramified microglia in rat cerebral cortex, and the quality was quite comparable to that obtained by an indirect fluorescent antibody technique (IFAT) and an avidin biotin-peroxidase complex method (ABCM). The DFAT also clearly stained activated microglia in axotomized rat facial nucleus, and the quality was equivalent to that obtained by the ABCM.
Prospective cohort study
The role of Tranexamic Acid in bleeding control during Total Hip Arthroplasty: An analysis
This prospective cohort study analyzed the role and use of tranexamic acid (ATX) in control of bleeding in patients undergoing primary total hip arthroplasty. The observation was based on administration of a single dose of venous tranexamic acid 20 mg per kg of weight of patients after anesthetic induction. A group of 40 patients admitted for the treatment of hip coxarthrosis during December 2017 to December 2019 were evaluated in this study. In this group, 20 patients used ATX and others were related in the control group.
Retrospective Study
Study of the efficiency of clinical examination in the diagnosis of meniscal injuries in patients submitted to knee arthroscopy in a University hospital
The aim of the present study was to evaluate the efficiency of knee physical examination routinely used in orthopedic clinical practice for the diagnose of meniscal injuries. This study was based on a review of medical records of patients submitted to knee arthroscopy to treatment meniscal lesions clinically diagnosed in the Gaffrèe & Guinle University Hospital at the knee outpatient clinic from 2011 to 2013.
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