In this paper we examine 20th century conceptual developments regarding dementia and the NDs, from the first recognition of their clinical and pathological characteristics, through recognition of their molecular and cellular attributes and, ultimately, to recognition of their dynamic and vascular origins. We introduce a new energybased causal model of these disabling neurologic conditions that provides vital insights into their origins and necessary treatment. The term ‘causal’ implies that future treatment of these conditions necessarily entails recognition and correction of underlying energy deficits.
WThe recent recognition of intravascular amyloid formation with deposition of insoluble microthrombi throughout the circulatory system in primary COVID-19 infection or following administration of mRNA vaccines is
a pivotal discovery that alters conventional notions about the nature of the underlying pathologic process at play in SARS-CoV-2 infection.
We report the case of 69 years old female with a history of uncontrolled type 2 diabetes, who presented refractory and chronic right-sided purulent otorrhea with temporal headaches for 6 months, treated with no improvement by multiple attempts of ambulatory empiric therapy.
Pseudomeningoceles are rare complications of laminectomy surgery. Such clinical condition results from an inadvertent surgical dural rupture. We describe in the present study the report of a patient who developed iatrogenic pseudomeningocele in the lumbar region after performing a left laminectomy in L5 topography.
Alzheimer’s disease (AD) is the most common degenerative brain disease in the aged population. By 2050, AD prevalence is expected to increase from 4.7 million (based on 2010 census) to 13.8 million people. It is characterized by the progressive decline of cognition and memory, as well as changes in behavior and personality.
This simple method specifically stained ramified microglia in rat cerebral cortex, and the quality was quite comparable to that obtained by an indirect fluorescent antibody technique (IFAT) and an avidin biotin-peroxidase complex method (ABCM).
Tuberous Sclerosis Complex or Bourneville’s disease is an autosomal dominant disease with high penetrance and variability characterized by multisystem involvement by benign lesions, originally defined by the classic triad of Vogt: sebaceous adenoma, epilepsy and mental retardation.
This is a report to create awareness among clinicians on a very rare condition of thunderclap headache. A 51-year-old lady presented with recurrent thunderclap headaches over the preceding 3 days. In this report, the clinical presentation, investigation and management for Reversible Cerebral Vasoconstriction Syndrome (RCVS) including its outcome are described.
Priapism as such is rare in spinal cord injury. It can be ischemic or non ischemic Priapism. The ischemic variety is painful and spontaneous while non ischemic is painless making diagnosis delayed. Penile gas gangrene in spinal cord injury is rare, but could be initiated in patients with ischemic Priapism as a triggering factor.
The Department of Neurology publishes rigorously peer-reviewed research across basic, translational and clinical Neurology. This multidisciplinary open-access domain is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.
The papers published encompass the entire field of neurology. The Department of Neurology welcomes papers that investigate and contribute to existing knowledge by publishing original research, reviews, case studies, prospective, retrospectives and all other studies dealing with clinical and basic research in neuroscience. This is the official specialty of The Gazette of Medical Sciences (TheGMS). The articles are accepted only for exclusive publication in TheGMS.
Authors are encouraged to submit clinical aspects of basic research and trials that will have an impact on the understanding of health and disease. Case reports, focused research on a broad range of disciplines as well as experimental papers may be submitted. Besides, authors may contribute short reviews (by invitation from the Editor) and letters to the editor. This journal adheres to the policies recommended by The Committee on Publication Ethics (COPE).
The Department of Neurology aims to publish articles of original, interdisciplinary, and translational research and to safeguard the scientific merit and clinical significance of its diverse content. The Department practices rigorous peer review of submitted papers and publishes the accepted papers in Open Access format with an aim to drive high visibility and global exposure of the scholar’s hard work.
The subject areas covered by Department of Neurology include, but are not limited to:
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