Advancing clinical research, disease prevention, diagnosis, and evidence-informed care across general internal medicine and its specialties.
Internal medicine is concerned with the prevention, diagnosis and nonsurgical management of diseases affecting adults, particularly conditions requiring comprehensive clinical assessment and long-term care. The Department of Internal Medicine of The Gazette of Medical Sciences (The GMS) welcomes scholarly contributions that advance the understanding of human disease, strengthen clinical decision-making and improve patient outcomes. Its scope includes general internal medicine, primary care, hospital medicine and the management of acute, chronic and complex medical conditions. Particular attention is given to research that integrates clinical findings, diagnostic evidence and individual patient circumstances into effective approaches to medical care.
Many patients present with overlapping symptoms, multiple chronic conditions or disorders involving several organ systems. The Department encourages investigations into cardiovascular, respiratory, renal, gastrointestinal, endocrine, infectious, haematological, rheumatological and metabolic diseases from the perspective of general medical practice. Research may address disease mechanisms, differential diagnosis, clinical manifestations, comorbidities, complications, prognosis and therapeutic management. Studies evaluating diagnostic accuracy, clinical guidelines, pharmacological interventions, medication safety, treatment monitoring and the coordination of care across specialties are particularly relevant.
Effective internal medicine extends beyond treating individual diseases to addressing the broader needs of patients and healthcare systems. Research concerning preventive medicine, multimorbidity, geriatric care, health literacy, patient communication, shared decision-making, quality of life and continuity of care is welcomed. The Department also considers investigations of hospital-based practice, healthcare delivery, clinical quality improvement, patient safety and evidence-based management protocols. Studies involving clinical epidemiology, population risk factors and the implementation of healthcare programmes may contribute valuable knowledge when they demonstrate relevance to everyday medical practice.
The Department welcomes original clinical research, observational studies, clinical trials, systematic and narrative reviews, short communications and well-documented case reports within the journal's applicable article categories. Translational investigations connecting experimental findings with clinical applications are also encouraged. Contributions involving diagnostic technologies, digital medicine, artificial intelligence and emerging therapeutic strategies should demonstrate clear clinical relevance and appropriately supported conclusions. Manuscripts are expected to present transparent methods, ethical considerations where applicable, and balanced interpretations of their findings. The Department aims to strengthen evidence-based medical practice through rigorous investigation and meaningful interdisciplinary exchange.
Interest in modulating the immune response beyond glucocorticoids has existed since the COVID-19 pandemic began. Recent trials have shown promising results with IL-6 inhibitors such as tocilizumab although similar data on Sarilumab is lacking. In this report, we analyze the current evidence on Sarilumab in hospitalized COVID-19 patients to evaluate its efficacy.
View / Download Article ↗It is said that no discovery is complete until its implications have been fully realized. The identification of a previously unrecognized phenomenon says little of its potential effects. What appears as a stroke of good luck can culminate in disaster; misfortune may harbor unimagined potential. Discovery is a double-edged sword that manifests only over time.
View / Download Article ↗Antibiotic drugs are the most frequently prescribed medications among hospitalized patients for life-saving purposes, mainly in immunocompromised patient, like in patient with end stage renal disease on hemodialysis (HD) or those who had documented bacterial infection.
View / Download Article ↗Please direct any enquiry or submit papers to: info@thegms.co
